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. 1970 Dec;7(6):839-49.

Production of 19S and 7S antibodies by cancer patients

A G Levin, M P Cunningham, A K Steers, D G Miller, C M Southam

Production of 19S and 7S antibodies by cancer patients

A G Levin et al. Clin Exp Immunol. 1970 Dec.

Abstract

The production of 7S and 19S antibody was compared in twenty-one patients with various types of carcinoma, four with lymphomatous neoplasms, and eleven healthy controls, at weekly intervals following administration of 17D yellow fever live virus vaccine. Sera were also tested for interferon and infectious virus. Mean and range of antibody titres were very similar in carcinoma patients and controls. There was a slight delay in antibody production in the cancer patients. Viraemia was demonstrated in 1/8 healthy controls, 4/20 carcinoma patients, and 2/3 lymphoma patients. No interferon was detected.

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