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. 1970 May;207(3):789-801.
doi: 10.1113/jphysiol.1970.sp009095.

Further study of the role of calcium in synaptic transmission

Further study of the role of calcium in synaptic transmission

B Katz et al. J Physiol. 1970 May.

Abstract

1. The effect of calcium on synaptic transmission has been studied by intracellular recording of pre- and post-synaptic potential changes in the stellate ganglion of the squid.2. For a given presynaptic ;input' (propagated spike, or local depolarizing pulse after tetrodotoxin treatment), the post-synaptic response increases with external calcium concentration [Ca](o) in a highly non-linear fashion, indicating that transmitter output varies with more than the second power of [Ca](o) over a certain concentration range.

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