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. 1970 Dec;24(4):705-11.
doi: 10.1038/bjc.1970.84.

Radiation-induced fibrosarcoma

N F Gane, R Lindup, P Strickland, M H Bennett
Free PMC article

Radiation-induced fibrosarcoma

N F Gane et al. Br J Cancer. 1970 Dec.
Free PMC article

Abstract

Six cases of fibrosarcoma arising in previously irradiated tissues are reported, out of a total of 220 cases of fibrosarcoma treated at Mount Vernon Hospital during the last 23 years.This rare occurrence may follow at any interval from 3 to 38 years after irradiation, usually after high dosage. Four of our six cases are known to have died of the disease.The literature regarding radiation-induced fibrosarcoma is reviewed and it is suggested that adequate excision or amputation may be curative, if undertaken early enough.

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