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. 1970 Dec;24(4):853-60.
doi: 10.1038/bjc.1970.101.

Studies of the rat immune response to plasmacytoma 5563 in C3H mice

O Fakhri, J R Hobbs
Free PMC article

Studies of the rat immune response to plasmacytoma 5563 in C3H mice

O Fakhri et al. Br J Cancer. 1970 Dec.
Free PMC article

Abstract

Washed lymphocytes from immunized rats showed no reaction against mouse plasmacytoma 5563 in vivo or in vitro.Cell-free lymph from immunized rats was shown to be cytotoxic to the tumour cells in vitro. This effect we have shown to be solely in the 19s fraction after Sephadex G-200 separation.This 19s fraction conferred partial protection to tumour bearing mice when given shortly after transplantation, but had negligible effect against late well established tumour.

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References

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