Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication
- PMID: 551247
- DOI: 10.1038/277192a0
Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication
Abstract
A fragment of HeLa cell mitochondrial DNA containing the origin of replicaton has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5'-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences.
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