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. 1979 Sep 27;281(5729):277-82.
doi: 10.1038/281277a0.

Two-step binding of eukaryotic ribosomes to brome mosaic virus RNA3

P Ahlquist, R Dasgupta, D S Shih, D Zimmern, P Kaesberg

Two-step binding of eukaryotic ribosomes to brome mosaic virus RNA3

P Ahlquist et al. Nature. .

Abstract

Although brome mosaic virus RNA3 has only one translatable cistron, it can bind two 80S ribosomes at initiation. One ribosome binds at the first AUG codon (base 92-94). The other binds nearer the 5' end at an entry or holding site. Disome formation is thus unrelated to a silent cistron approximately 1,000 bases downstream.

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