Two-step binding of eukaryotic ribosomes to brome mosaic virus RNA3
- PMID: 551276
- DOI: 10.1038/281277a0
Two-step binding of eukaryotic ribosomes to brome mosaic virus RNA3
Abstract
Although brome mosaic virus RNA3 has only one translatable cistron, it can bind two 80S ribosomes at initiation. One ribosome binds at the first AUG codon (base 92-94). The other binds nearer the 5' end at an entry or holding site. Disome formation is thus unrelated to a silent cistron approximately 1,000 bases downstream.
Similar articles
-
Nucleotide sequence of a viral RNA fragment that binds to eukaryotic ribosomes.Nature. 1975 Aug 21;256(5519):624-8. doi: 10.1038/256624a0. Nature. 1975. PMID: 807854
-
Binding of ribosomes to 5'-terminal leader sequences of eukaryotic messenger RNAs.Proc Natl Acad Sci U S A. 1979 Jul;76(7):3111-5. doi: 10.1073/pnas.76.7.3111. Proc Natl Acad Sci U S A. 1979. PMID: 290990 Free PMC article.
-
Formation of ribosome-RNA initiation complexes with alfalfa mosaic virus RNA 4 and RNA 3.Nucleic Acids Res. 1979 Sep 11;7(1):151-66. doi: 10.1093/nar/7.1.151. Nucleic Acids Res. 1979. PMID: 114984 Free PMC article.
-
How do eucaryotic ribosomes select initiation regions in messenger RNA?Cell. 1978 Dec;15(4):1109-23. doi: 10.1016/0092-8674(78)90039-9. Cell. 1978. PMID: 215319 Review. No abstract available.
-
Mechanism of mRNA recognition by eukaryotic ribosomes during initiation of protein synthesis.Curr Top Microbiol Immunol. 1981;93:81-123. doi: 10.1007/978-3-642-68123-3_5. Curr Top Microbiol Immunol. 1981. PMID: 7026182 Review. No abstract available.
Cited by
-
Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems.Mol Cell Biol. 1989 Nov;9(11):5073-80. doi: 10.1128/mcb.9.11.5073-5080.1989. Mol Cell Biol. 1989. PMID: 2601709 Free PMC article.
-
Regulation of brome mosaic virus gene expression by restriction of initiation of protein synthesis.J Virol. 1980 May;34(2):330-5. doi: 10.1128/JVI.34.2.330-335.1980. J Virol. 1980. PMID: 16789194 Free PMC article.
-
Genomic RNA of mengovirus V. Recognition of common features by ribosomes and eucaryotic initiation factor 2.J Virol. 1982 Jan;41(1):30-41. doi: 10.1128/JVI.41.1.30-41.1982. J Virol. 1982. PMID: 6283122 Free PMC article.
-
Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA.Proc Natl Acad Sci U S A. 1982 Sep;79(17):5235-9. doi: 10.1073/pnas.79.17.5235. Proc Natl Acad Sci U S A. 1982. PMID: 6291034 Free PMC article.
-
Multiple proteins and subgenomic mRNAs may be derived from a single open reading frame on tobacco mosaic virus RNA.Nucleic Acids Res. 1983 Feb 11;11(3):801-21. doi: 10.1093/nar/11.3.801. Nucleic Acids Res. 1983. PMID: 6835837 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources