Correlation of mixed-function oxidase activity with ultrastructural changes in the liver of a marine fish
- PMID: 552910
Item in Clipboard
Correlation of mixed-function oxidase activity with ultrastructural changes in the liver of a marine fish
Cancer Biochem Biophys.
1979.
Abstract
Specimens of mullet (Mugil cephalus), a marine fish, were given single doses of 3-methylcholanthrene intraperitoneally and the activity of the microsomal mixed-function oxygenase system in the liver was measured by the metabolism of benzo(a)pyrene. The enzyme system was found to be inducible with concomitant ultrastructural changes in the hepatocytes. The specific activity and the metabolic profile approximate those of the rat.
Similar articles
-
Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine.Drug Metab Dispos. 1974 Nov-Dec;2(6):545-555. Drug Metab Dispos. 1974. PMID: 4156316 No abstract available.
-
[Selective induction of a liver microsomal mixed-function oxygenase system. II. Kinetic study of benz(a)pyrene hydroxylase].Arch Int Physiol Biochim. 1974 Feb;82(1):199. Arch Int Physiol Biochim. 1974. PMID: 4136435 French. No abstract available.
-
Benzo[a]pyrene metabolism in marine fish and some analytical aspects of its metabolites.Natl Cancer Inst Monogr. 1984 May;65:391-6. Natl Cancer Inst Monogr. 1984. PMID: 6087146
-
The liver microsomal hydroxylation enzyme system. Induction and properties of the functional components.Front Gastrointest Res. 1976;2:1-31. Front Gastrointest Res. 1976. PMID: 819342 Review. No abstract available.
-
Species differences in microsomal monooxygenase activity and their relationship to biological half-lives.Drug Metab Rev. 1978;7(2):295-323. doi: 10.3109/03602537808993770. Drug Metab Rev. 1978. PMID: 354914 Review. No abstract available.
Cited by
-
Normal versus abnormal structure: considerations in morphologic responses of teleosts to pollutants.Environ Health Perspect. 1987 Apr;71:139-46. doi: 10.1289/ehp.8771139. Environ Health Perspect. 1987. PMID: 3297656 Free PMC article. Review.