Immunochemical analysis of distinct cellular antigens isolated from a nontypable bovine strain of group B streptococci
- PMID: 55388
- PMCID: PMC420578
- DOI: 10.1128/iai.13.1.69-77.1976
Immunochemical analysis of distinct cellular antigens isolated from a nontypable bovine strain of group B streptococci
Abstract
Four immunologically distinct antigens were isolated from a bovine strain of group B streptococci, designated 14 Mi. Chemical analysis indicated that two of the cell surface antigens consisted of glucose, galactose, and glucosamine, whereas the other cell surface antigen, an acidic protein, contained a predominance of aspartic acid, glutamic acid, and alanine. A cell wall-associated triheteroglycan consisting of galactose, glucose, and glucosamine was isolated from strain 14 Mi by 10% trichloroacetic acid. Immunochemical studies suggested that this glycan is type specific and consists of an immunodominant alpha-linked galactosyl-glucose disaccharide.
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