Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Jan;11(1):110-22.
doi: 10.1016/S0006-3495(71)86199-4.

Independence of the sodium and potassium conductance channels. A kinetic argument

R C Hoyt

Independence of the sodium and potassium conductance channels. A kinetic argument

R C Hoyt. Biophys J. 1971 Jan.

Abstract

Tightly coupled models for the sodium and potassium conductance changes, in which the potassium "on" process is intimately related to the sodium "on" and "off" processes, are studied. It is shown that such coupled models are incapable of simultaneously showing the observed effects of conditioning potentials on sodium inactivation and on the translation of the potassium conductance in time. It is concluded that the primary mechanisms for the sodium and potassium channels are probably independent.

PubMed Disclaimer

References

    1. J Gen Physiol. 1969 Jun;53(6):685-703 - PubMed
    1. J Gen Physiol. 1968 Sep 1;52(3):553-5 - PubMed
    1. Biophys J. 1970 Jul;10(7):610-7 - PubMed
    1. Biophys J. 1963 Sep;3:399-431 - PubMed
    1. J Gen Physiol. 1960 May;43:105-17 - PubMed

LinkOut - more resources