Comparative Study
["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)]
[Article in
French]
- PMID: 554102
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Comparative Study
["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)]
[Article in
French]
Nouv Presse Med.
.
Abstract
As first described in serious systemic illnesses isolated decreased T3 plasma concentration was related to impaired peripheral conversion of T4, to T3 with preferential production of reverse T3 (rT3). A "low T3 syndrome" was seen in 47 out of 109 patients with extra-thyroidal diseases. Metabolic state, TSH and TSH responses to TRH were normal despite of low T3 concentration. Euthyroidism seems mainly due to T4 itself in these patients.
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