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. 1971 Mar 5;171(3974):910-1.
doi: 10.1126/science.171.3974.910.

Ethacrynic acid effect on the composition of cochlear fluids

E S Cohn, E H Gordes, S W Brusilow

Ethacrynic acid effect on the composition of cochlear fluids

E S Cohn et al. Science. .

Abstract

Ethacrynic acid, when administered to six dogs, caused a fall in the concentration of potassium in endolymph from 145 to 21 milliequivalents per liter and a rise in the concentration of sodium from 5.9 to 146 milliequivalents per liter. The composition of perilymph is unaffected. Perilymph and endolymph are slightly hypertonic as compared to plasma.

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