Review
doi: 10.1016/0091-6749(76)90029-4.
Differential cellular immune responsiveness to systems of the major histocompatibility complex
- PMID: 55429
- DOI: 10.1016/0091-6749(76)90029-4
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Review
Differential cellular immune responsiveness to systems of the major histocompatibility complex
J Allergy Clin Immunol.
1976 Feb.
Abstract
Antigens determined by genes of the major histocompatibility complex can be divided into two systems" the LD (lymphocyte-defined or L determinant) and SD (serologically defined or S determinant) antigens. This division is based on the differential cellular responsiveness to these two sets of antigens of two subpopulations of T lymphocytes: a proliferating helper cell responds primarily to the LD antigens while a cytotoxic T lymphocyte responds most strongly to the SD antigens.
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