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. 1971 Mar 19;171(3976):1163-5.
doi: 10.1126/science.171.3976.1163.

Immunoglobulin M and secretory immunoglobulin A: presence of a common polypeptide chain different from light chains

J Mestecky, J Zikan, W T Butler

Immunoglobulin M and secretory immunoglobulin A: presence of a common polypeptide chain different from light chains

J Mestecky et al. Science. .

Abstract

Unique polypeptide chains have been isolated from S-sulfonated light-chain fractions of human serum immunoglobulin M and colostral immunoglobulin A. Their electrophoretic mobilities, molecular weights, peptide maps, amino acid compositions, and antigenic determinants are very similar or perhaps identical but differ from those of light chains and secretory piece.

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