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. 1971 Mar 26;171(3977):1248-50.
doi: 10.1126/science.171.3977.1248.

Synaptic facilitation: long-term neuromuscular facilitation in crustaceans

R G Sherman, H L Atwood

Synaptic facilitation: long-term neuromuscular facilitation in crustaceans

R G Sherman et al. Science. .

Abstract

Continuous stimulation at frequencies equal to or greater than 5 hertz for 20 to 30 minutes results in a two- to fivefold increase in the amplitudes of excitatory postsynaptic potential recorded from certain stretcher and opener muscles of decapod crustaceans. This long-term facilitation appears to result from an accumulation of sodium ions within the nerve terminals. It persists for at least 1 hour after stimulation has stopped.

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