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Case Reports
. 1976 Jan;138(1):19-23.

The endoscopic appearance of the duodenum in Whipple's disease

  • PMID: 55512
Case Reports

The endoscopic appearance of the duodenum in Whipple's disease

N A Volpicelli et al. Johns Hopkins Med J. 1976 Jan.

Abstract

Duodenoscopic examination of a patient with Whipple's disease revealed that the duodenal mucosa appeared to be partially covered with a yellow-white material. On closer inspection, however, this was found to consist of enlarged villi interspersed with normal-looking mucosa. Histologically these enlarged white villi were shown to contain a heavy accumulation of lipid and typical PAS positive macrophages. The duodenal mucosa was endoscopically normal and histologically showed only a few PAS positive macrophages one year after instituting antibiotic therapy.

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