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. 1971 Jul 17;3(5767):159-60.
doi: 10.1136/bmj.3.5767.159.

Trimethoprim-sulphamethoxazole in acute brucellosis

A Hassan, M M Erian, Z Farid, S D Hathout, K Sorensen

Trimethoprim-sulphamethoxazole in acute brucellosis

A Hassan et al. Br Med J. .

Abstract

Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within three weeks of ending treatment. There were no side effects of the treatment. It is suggested that the treatment be continued for at least six weeks to prevent relapses.

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