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. 1971 Aug;46(248):525-7.
doi: 10.1136/adc.46.248.525.

Failure of a massive single oral dose of vitamin A to prevent deficiency

S M Pereira, A Begum

Failure of a massive single oral dose of vitamin A to prevent deficiency

S M Pereira et al. Arch Dis Child. 1971 Aug.

Abstract

Preschool children maintained on low and moderate carotene diets were given a single oral dose of 50,000 μg vitamin A palmitate.

On the low carotene diet, xerosis was observed in 8 weeks' time in the control group of children, and in 10 weeks' time in the children given the load of vitamin A. Statistical differences in serum vitamin A values between the groups were not of significance after 18 weeks.

Children on a moderate carotene diet did not benefit from the loading dose of vitamin A.

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References

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