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. 1977 Jan 21;195(4275):307-9.
doi: 10.1126/science.556653.

Lateral transport of a lipid probe and labeled proteins on a cell membrane

J Schlessinger, D Axelrod, D E Koppel, W W Webb, E L Elson

Lateral transport of a lipid probe and labeled proteins on a cell membrane

J Schlessinger et al. Science. .

Abstract

Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.

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