Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Jun;34(3):224-5.
doi: 10.1136/jnnp.34.3.224.

Uptake and release of 14 C-5-hydroxytryptamine by platelets in affective illness

D M Shaw, D A MacSweeney, N Woolcock, A B Bevan-Jones

Uptake and release of 14 C-5-hydroxytryptamine by platelets in affective illness

D M Shaw et al. J Neurol Neurosurg Psychiatry. 1971 Jun.

Abstract

In the search for paradigms of postulated abnormalities in indolamine function in the brain in affective disorders, 5-HT uptake and release was estimated in platelets from patients suffering from severe depressive illness. Neither of these measures was altered by the illness and the most likely explanation for the negative findings was that in this setting platelets are not a suitable model.

PubMed Disclaimer

References

    1. Br J Psychiatry. 1965 Oct;111(479):993-8 - PubMed
    1. Br J Pharmacol Chemother. 1968 Jan;32(1):1-16 - PubMed

LinkOut - more resources