doi: 10.1126/science.172.3986.947.
Synthesis of 5S and 4S RNA in metaphase-arrested HeLa cells
- PMID: 5573566
- DOI: 10.1126/science.172.3986.947
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Synthesis of 5S and 4S RNA in metaphase-arrested HeLa cells
Science.
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Abstract
The continued synthesis of both 5S and 4S RNA in metaphase-arrested HeLa cells is demonstrated; 5S RNA is apparently synthesized at approximately 74 percent of the interphase rate, while 4S RNA is synthesized at approximately one-third the rate. The ratio of uridine incorporation to RNA methylation is used to correct for the alteration in the specific activity of the pyrimidine pool during metaphase arrest.
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