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. 1971 Jun 4;172(3987):1058-60.
doi: 10.1126/science.172.3987.1058.

Hycanthone: a frameshift mutagen

P E Hartman, K Levine, Z Hartman, H Berger

Hycanthone: a frameshift mutagen

P E Hartman et al. Science. .

Abstract

Rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely related compound, miracil D, is nonmutagenic in Salmonella. Both hycanthone and miracil D are frameshift mutagens for T4 bacteriophage during growth in Escherichia coli.

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