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. 1976 Mar 6;1(7958):499-501.
doi: 10.1016/s0140-6736(76)90291-9.

Serum-high-density-lipoprotein and atherosclerotic heart-disease

K Berg, A L Borresen

Serum-high-density-lipoprotein and atherosclerotic heart-disease

K Berg et al. Lancet. .

Abstract

Serum-high-density-lipoprotein (H.D.L.) concentrations were determined in 49 men who had had a myocardial infarction and in 102 healthy, middle-aged men, all from Northern Sweden. A quantitative immunological assay based on a monospecific antiserum to the main polypeptide (apoprotein A-I) of H.D.L. was used. The mean H.D.L. concentration was significantly lower in the men with coronary heart-disease than in the controls. The results accord with the hypothesis that high levels of H.D.L. to some extent protect against ischaemic heart-disease.

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