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. 1976 Mar 6;1(7958):506-8.
doi: 10.1016/s0140-6736(76)90294-4.

HLA-DW3 associated with coeliac disease

J J Keuning, A S Peña, A van Leeuwen, J P van Hooff, J J va Rood

HLA-DW3 associated with coeliac disease

J J Keuning et al. Lancet. .

Abstract

28 patients with coeliac disease (C.D.) were typed for the HLA-A, -B, and -D loci by several techniques. It was found that C.D. is primarily associated with the DW3 determinant and only secondarily with HLA-B8. The previously described association with HLA-B8 is explained by linkage disequilibrium between HLA-B8 and DW3.

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