Response of aspirin-allergic patients to challenge by some analgesics in common use
- PMID: 5579491
- PMCID: PMC1796028
- DOI: 10.1136/bmj.2.5760.494
Response of aspirin-allergic patients to challenge by some analgesics in common use
Abstract
Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics. Marked falls in FEV(1) were observed after ingestion of paracetamol, indomethacin, mefenamic acid, and dextropropoxyphene in some subjects. The mechanisms of analgesic-induced asthma are discussed: it is believed to be a non-immunological process of great practical importance when prescribing analgesics to asthmatics.
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