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. 1967 Dec;1(6):1217-23.
doi: 10.1128/JVI.1.6.1217-1223.1967.

Isolation and partial characterization of nucleic acid of influenza virus

Isolation and partial characterization of nucleic acid of influenza virus

D P Nayak et al. J Virol. 1967 Dec.

Abstract

The principal ribonucleic acid (RNA) component isolated from purified equine influenza virus has an approximate sedimentation coefficient (S(20,W)) of 21S in sucrose gradient containing 0.1 m NaCl. Three other components of 18S, 14S, and 8S were also detected. All the RNA components have characteristics of single-stranded RNA. The average base composition of the principal RNA components is cytosine, 22.2; adenine, 22.9; guanine, 22.3; and uridine, 32.6. There was no qualitative difference in the RNA isolated from noninfectious virus particles compared to that from infectious virions.

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