doi: 10.1016/0092-8674(77)90284-7.
Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells
- PMID: 562721
- DOI: 10.1016/0092-8674(77)90284-7
Item in Clipboard
Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells
Cell.
1977 Nov.
Abstract
n-Butyrate in low concentrations stops reversibly the proliferation of chick embryonic fibroblasts and of HeLa cells, shutting off DNA synthesis. Extensive acetylation of histones is seen at the same time as inhibition of DNA synthesis. Nuclei from n-butyrate-treated HeLa cells remain inactive in control cytosol; control nuclei are strongly inhibited by cytosol from treated cells.
Similar articles
-
The gross level of in vitro RNA synthesis in HeLa nuclei is unaltered by histone hyperacetylation.Biochem Biophys Res Commun. 1979 Oct 12;90(3):917-24. doi: 10.1016/0006-291x(79)91915-6. Biochem Biophys Res Commun. 1979. PMID: 508354 No abstract available.
-
Stimulation of DNA synthesis in isolated HeLa nuclei by calf thymus histones.Biochem Biophys Res Commun. 1974 Apr 8;57(3):635-40. doi: 10.1016/0006-291x(74)90593-2. Biochem Biophys Res Commun. 1974. PMID: 4857146 No abstract available.
-
Acetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cells.J Biol Chem. 1983 Jan 25;258(2):1299-304. J Biol Chem. 1983. PMID: 6822500
-
[Molecular and cellular action of butyrate].C R Seances Soc Biol Fil. 1992;186(1-2):12-25. C R Seances Soc Biol Fil. 1992. PMID: 1450986 Review. French.
-
The regulation of DNA synthesis in eukaryotes.Adv Cell Biol. 1971;2:1-46. doi: 10.1007/978-1-4615-9588-5_1. Adv Cell Biol. 1971. PMID: 4949654 Review. No abstract available.
Cited by
-
Regulation of the induction of alkaline phosphatase in choriocarcinoma cells by sodium butyrate.In Vitro. 1979 Oct;15(10):789-95. doi: 10.1007/BF02618305. In Vitro. 1979. PMID: 42610
-
Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate.Nucleic Acids Res. 1983 Nov 11;11(21):7631-48. doi: 10.1093/nar/11.21.7631. Nucleic Acids Res. 1983. PMID: 6316266 Free PMC article.
-
Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success.Bioessays. 2016 Nov;38(11):1102-1110. doi: 10.1002/bies.201600070. Epub 2016 Sep 22. Bioessays. 2016. PMID: 27717012 Free PMC article. Review.
-
Fiber and cancer.Med Oncol Tumor Pharmacother. 1990;7(2-3):137-41. doi: 10.1007/BF02988541. Med Oncol Tumor Pharmacother. 1990. PMID: 2172667 Review.
-
Independent regulation by sodium butyrate of gonadotropin alpha gene expression and cell cycle progression in HeLa cells.Mol Cell Biol. 1984 May;4(5):829-39. doi: 10.1128/mcb.4.5.829-839.1984. Mol Cell Biol. 1984. PMID: 6203027 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
