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. 1968 Jan;106(2):425-30.
doi: 10.1042/bj1060425.

Hydrocortisone requirement for the induction of glutamine synthetase in chick-embryo retinas

L Reif-Lehrer, H Amos

Hydrocortisone requirement for the induction of glutamine synthetase in chick-embryo retinas

L Reif-Lehrer et al. Biochem J. 1968 Jan.

Abstract

Hydrocortisone has been found to induce glutamine synthetase activity in chick-embryo retinas in culture. Evidence is presented to show that the hydrocortisone is definitely required for transcription; its requirement for translation has not been ruled out. The possible identity of hydrocortisone with an active component of calf-serum diffusate reported earlier is discussed. The data also indicate that the glutamine synthetase messenger RNA is stable for at least several hours.

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