doi: 10.1038/271329a0.
X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro
- PMID: 563984
- DOI: 10.1038/271329a0
Item in Clipboard
X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro
Nature.
.
Abstract
Evidence is presented that both X chromosomes are genetically active in clonal cultures of undifferentiated female mouse teratocarcinoma stem cells derived from a spontaneous ovarian tumour. As the cells differentiate in vitro one of the X chromosomes becomes inactivated.
Similar articles
-
Genetic activity of X chromosomes in pluripotent female teratocarcinoma cells and their differentiated progeny.Cell. 1980 Sep;21(2):357-64. doi: 10.1016/0092-8674(80)90472-9. Cell. 1980. PMID: 7407917
-
Studies of the temporal relationship between the cytogenetic and biochemical manifestations of X-chromosome inactivation during the differentiation of LT-1 teratocarcinoma stem cells.Dev Biol. 1984 Jun;103(2):425-33. doi: 10.1016/0012-1606(84)90330-0. Dev Biol. 1984. PMID: 6724137
-
[The behavior of the X chromosomes in intra- and interspecific hybrid cells of murine teratocarcinoma PCC4azal].Ontogenez. 1991 Mar-Apr;22(2):158-67. Ontogenez. 1991. PMID: 1857596 Russian.
-
The role of sex chromosomes in mammalian germ cell differentiation: can the germ cells carrying X and Y chromosomes differentiate into fertile oocytes?Asian J Androl. 2015 May-Jun;17(3):360-6. doi: 10.4103/1008-682X.143306. Asian J Androl. 2015. PMID: 25578929 Free PMC article. Review.
-
Karyotype-phenotype correlation in females with X chromosome abnormalities.Ann N Y Acad Sci. 1997 Jun 17;816:373-7. doi: 10.1111/j.1749-6632.1997.tb52164.x. Ann N Y Acad Sci. 1997. PMID: 9238290 Review.
Cited by
-
Methylation of the mouse hprt gene differs on the active and inactive X chromosomes.Mol Cell Biol. 1986 Mar;6(3):914-24. doi: 10.1128/mcb.6.3.914-924.1986. Mol Cell Biol. 1986. PMID: 3022138 Free PMC article.
-
Analysis of the Xist RNA isoforms suggests two distinctly different forms of regulation.Mamm Genome. 2005 Jun;16(6):391-404. doi: 10.1007/s00335-004-2464-3. Mamm Genome. 2005. PMID: 16075366
-
The William Allan memorial award address: X-chromosome inactivation and the location and expression of X-linked genes.Am J Hum Genet. 1988 Jan;42(1):8-16. Am J Hum Genet. 1988. PMID: 3276178 Free PMC article. Review. No abstract available.
-
Variable X chromosome inactivation patterns in near-tetraploid murine EC x somatic cell hybrid cells differentiated in vitro.Genetica. 1993;88(2-3):107-17. doi: 10.1007/BF02424467. Genetica. 1993. PMID: 8224851
-
Female mice lacking Xist RNA show partial dosage compensation and survive to term.Genes Dev. 2016 Aug 1;30(15):1747-60. doi: 10.1101/gad.281162.116. Genes Dev. 2016. PMID: 27542829 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials
