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. 1978 Feb;62(2):303-5.
doi: 10.1111/j.1476-5381.1978.tb08460.x.

The effect of baclofen on alpha-flupenthixol-induced catalepsy in the rat

J A Davies, J Williams

The effect of baclofen on alpha-flupenthixol-induced catalepsy in the rat

J A Davies et al. Br J Pharmacol. 1978 Feb.

Abstract

1 alpha-Flupenthixol (alpha-FPT; 0.2 mg/kg i.p.) when administered to rats produced catalepsy. 2 Baclofen (10 mg/kg i.p.) given 30 min after alpha-FPT had a biphasic effect on the catalepsy. Initially there was a potentiation of the effect, followed by a significant attenuation of the degree of catalepsy. 3 Possible mechanisms of action are discussed.

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References

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