Mechanism of alpha-glycerophosphate regulation of acetyl-coenzyme A carboxylase of Saccharomyces cerevisiae
- PMID: 5643049
- PMCID: PMC252135
- DOI: 10.1128/jb.95.3.1090-1093.1968
Mechanism of alpha-glycerophosphate regulation of acetyl-coenzyme A carboxylase of Saccharomyces cerevisiae
Abstract
The mechanism proposed for the activation of animal acetyl-coenzyme A (CoA) carboxylase by alpha-glycerophosphate, namely, the removal of inhibitory palmityl-CoA via glyceride synthesis, is not the only possible one in the yeast system because extracts exhibiting marked stimulation of acetyl-CoA carboxylase activity by alpha-glyerophosphate show a lack of acyl-CoA compounds.
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