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. 1968 Apr 26;160(3826):427-8.
doi: 10.1126/science.160.3826.427.

Dimethyl sulfoxide: interactions with aromatic hydrocarbons

J J Kocsis, S Harkaway, M C Santoyo, R Snyder

Dimethyl sulfoxide: interactions with aromatic hydrocarbons

J J Kocsis et al. Science. .

Abstract

Dimethyl sulfoxide (DMSO) enhanced the hypertaurinuria produced by benzene, chlorobenzene, and toluene in rats. Undiluted DMSO was more effective than DMSO diluted with water in potentiating the toxicity of benzene in both rats and mice. Supernatants (9000g) prepared from livers of rats treated with DMSO 24 hours earlier metabolized more benzene than those from control rats.

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