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. 1978 Mar;84(1):95-102.
doi: 10.1111/j.1432-1033.1978.tb12145.x.

Association of DNA polymerase with nucleosomes from mammalian cell chromatin

E J Schlaeger, H J van Telgen, K H Klempnauer, R Knippers
Free article

Association of DNA polymerase with nucleosomes from mammalian cell chromatin

E J Schlaeger et al. Eur J Biochem. 1978 Mar.
Free article

Abstract

More than half of the DNA polymerase beta in mouse ascites cell chromatin was found to be associated with monomeric nucleosomal particles (produced by micrococcal nuclease treatment of chromatin). Almost all nuclear DNA polymerase activity in lymphocytes was found to be associated with nucleosomes. The nucleosome-associated enzyme was mainly DNA polymerase beta in chromatin from resting and mainly DNA polymerase alpha in chromatin from concanavalin-A-stimulated lymphocytes.

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