Large Y chromosome (Yq+) and increased risk of abortion
- PMID: 566178
- DOI: 10.1111/j.1399-0004.1978.tb04140.x
Large Y chromosome (Yq+) and increased risk of abortion
Abstract
Previous reports have indicated an association between Yq+ in the family and increased risk of abortion. In a chromosome investigations of 11,148 consecutively newborn children, we found 58 boys with a large Y chromosome (Y/F equal to or greater than 1.00). The mothers of these boys had 22% abortions, compared with 13% among 4,895 mothers of children with normal karyotypes and without Yq+ (P less than 0.001).
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