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. 1968 Jul 13;3(5610):96-7.
doi: 10.1136/bmj.3.5610.96.

Oxytocinase in plasma and placenta in normal and prolonged labour

V S Mathur, J M Walker

Oxytocinase in plasma and placenta in normal and prolonged labour

V S Mathur et al. Br Med J. .

Abstract

In prolonged labour (dystocia) the level of activity of the enzyme oxytocinase is increased in the plasma and decreased in the placenta; the ratio of its activity in the placenta to that in plasma is less than half that found in normal labour. A possible explanation is that oxytocinase is derived mainly from the placenta and that during prolonged labour the enzyme escapes into the maternal blood stream.

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