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. 1968 Jul 27;3(5612):222-3.
doi: 10.1136/bmj.3.5612.222.

Electrocardiographic changes in amitriptyline poisoning

R J Barnes, S M Kong, R W Wu

Electrocardiographic changes in amitriptyline poisoning

R J Barnes et al. Br Med J. .

Abstract

In imipramine and amitriptyline poisoning the electrocardiographic abnormalities comprise arrhythmias, widening of the QRS complex, and marked changes in die S-T segment. These features were found to be of value in the differential diagnosis of unknown poisoning. The unusual configuration of qR with raised S-T segment in V1, simulating myocardial infarction, was seen in one of our patients and has been noted in four cases reported by other workers.

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