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. 1968 Jul;108(4):533-9.
doi: 10.1042/bj1080533.

Biosynthesis of putrescine in the prostate gland of the rat

A E Pegg, H G Williams-Ashman

Biosynthesis of putrescine in the prostate gland of the rat

A E Pegg et al. Biochem J. 1968 Jul.

Abstract

In the rat ventral prostate gland the biosynthesis of putrescine, a precursor of spermidine and spermine, is shown to occur by the direct decarboxylation of l-ornithine. Some properties of a soluble pyridoxal phosphate-dependent l-ornithine decarboxylase are described. The findings are discussed in relation to other enzymic reactions involved in the biosynthesis of polyamines by the prostate gland.

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