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. 1978 Jun;13(6):451-4.
doi: 10.1007/BF02533717.

Gangliosides of cultured cells of a rat mammary carcinoma cell line

T W Keenan, E Schmid, W W Franke

Gangliosides of cultured cells of a rat mammary carcinoma cell line

T W Keenan et al. Lipids. 1978 Jun.

Abstract

Ganglioside content of rat mammary carcinoma-derived cells grown in layers in vitro was nearly as high as that of apical membrane-derived milk fat globule membrane and nearly four time higher than the content of normal, lactating mammary tissue on a protein basis. The major ganglioside of these carcinoma-derived cells was identified as GDla (sialic acid-Gal-GalNAc-sialic acid)-Gal-Glc-Cer. Relative to carcinoma-derived cells, rat mammary tissue and milk fat globule membrane had more complex ganglioside patterns but appeared to lack substantial quantities of GDla.

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