doi: 10.1126/science.162.3851.377.
Hypothalamic motivational systems: fixed or plastic neural circuits?
- PMID: 5677536
- DOI: 10.1126/science.162.3851.377
Item in Clipboard
Hypothalamic motivational systems: fixed or plastic neural circuits?
Science.
.
Abstract
Eating and drinking were elicited by electrical stimulation through the same electrode in the hypothalamus of a satiated rat. Intensity thresholds for eliciting eating and drinking were different, and both thresholds decreased with repeated testing. These findings suggest an alternative to the hypothesis that the neural organization of hypothalamic drive systems is modified by experience.
Similar articles
-
Modification of motivated behavior elicited by electrical stimulation of the hypothalamus.Science. 1968 Mar 8;159(3819):1119-21. doi: 10.1126/science.159.3819.1119. Science. 1968. PMID: 5636350
-
Lateral hypothalamic stimulation in satiated rats: the rewarding effects of self-induced drinking.Science. 1967 Sep 1;157(3792):1077-9. doi: 10.1126/science.157.3792.1077. Science. 1967. PMID: 6036241
-
[14C]Deoxyglucose mapping of first-order projections activated by stimulation of lateral hypothalamic sites eliciting gnawing, eating, and drinking in rats.J Comp Neurol. 1980 Dec 1;194(3):617-38. doi: 10.1002/cne.901940309. J Comp Neurol. 1980. PMID: 7451685
-
Reexamination of the role of the hypothalamus in motivation.Psychol Rev. 1970 Jan;77(1):16-31. doi: 10.1037/h0028581. Psychol Rev. 1970. PMID: 4908030 Review. No abstract available.
-
Hypothalamic regulation of food intake.Ideggyogy Sz. 2003 Sep 20;56(9-10):288-302. Ideggyogy Sz. 2003. PMID: 14608950 Review.
Cited by
-
Forebrain substrates of reward and motivation.J Comp Neurol. 2005 Dec 5;493(1):115-21. doi: 10.1002/cne.20689. J Comp Neurol. 2005. PMID: 16254990 Free PMC article. Review.
-
Feeding and drinking following stimulation of the diencephalon of the monkey with amines and other substances.Exp Brain Res. 1969;8(4):295-310. doi: 10.1007/BF00234377. Exp Brain Res. 1969. PMID: 4979902 No abstract available.
-
Self-stimulation: a rewarding decade.J Psychiatry Neurosci. 1991 Sep;16(3):109-14. J Psychiatry Neurosci. 1991. PMID: 1958643 Free PMC article. Review.
-
The inhibitory circuit architecture of the lateral hypothalamus orchestrates feeding.Science. 2013 Sep 27;341(6153):1517-21. doi: 10.1126/science.1241812. Science. 2013. PMID: 24072922 Free PMC article.
-
Lateral Hypothalamic Control of the Ventral Tegmental Area: Reward Evaluation and the Driving of Motivated Behavior.Front Syst Neurosci. 2017 Jul 6;11:50. doi: 10.3389/fnsys.2017.00050. eCollection 2017. Front Syst Neurosci. 2017. PMID: 28729827 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
