The insensitivity of mushroom nuclear RNA polymerase activity to inhibition by amatoxins
- PMID: 567964
- DOI: 10.1007/BF00429124
The insensitivity of mushroom nuclear RNA polymerase activity to inhibition by amatoxins
Abstract
Nuclear fractions isolated from Amanita phalloides, Amanita muscaria and Agaricus bisporus were subjected to in vitro RNA synthesis assays in the presence of various concentrations of amatoxins. The mushroom nuclei were highly insensitive to inhibition by amatoxin when compared to assays of nuclear fractions isolated from the Oömycete fungus, Achlya ambisexualis and from rabbit brain.
Similar articles
-
alpha-Amanitin-resistant RNA polymerase II from carpophores of Amanita species accumulating amatoxins.Biochim Biophys Acta. 1980 Mar 28;607(1):102-14. doi: 10.1016/0005-2787(80)90224-5. Biochim Biophys Acta. 1980. PMID: 7189412
-
Occurrence of amatoxins in Amanita ocreata.Lloydia. 1976 Sep-Oct;39(5):368-71. Lloydia. 1976. PMID: 1035403 No abstract available.
-
Purification and characterization of RNA polymerase II resistant to alpha-amanitin from the mushroom Agaricus bisporus.Biochemistry. 1979 Mar 6;18(5):795-803. doi: 10.1021/bi00572a009. Biochemistry. 1979. PMID: 570413
-
Amatoxin-Containing Mushroom Poisonings: Species, Toxidromes, Treatments, and Outcomes.Wilderness Environ Med. 2018 Mar;29(1):111-118. doi: 10.1016/j.wem.2017.10.002. Epub 2018 Jan 8. Wilderness Environ Med. 2018. PMID: 29325729 Review.
-
[Application of amanita toxic peptides in life sciences research].Wei Sheng Yan Jiu. 1999 Jan 30;28(1):60-3. Wei Sheng Yan Jiu. 1999. PMID: 12712754 Review. Chinese.
Cited by
-
Ulcerating Ileocolitis in Severe Amatoxin Poisoning.Case Rep Gastrointest Med. 2015;2015:632085. doi: 10.1155/2015/632085. Epub 2015 Aug 18. Case Rep Gastrointest Med. 2015. PMID: 26357578 Free PMC article.
-
Acute Liver Failure Caused by Amanita phalloides Poisoning.Int J Hepatol. 2012;2012:487480. doi: 10.1155/2012/487480. Epub 2012 Jul 3. Int J Hepatol. 2012. PMID: 22811920 Free PMC article.
-
Unique amanitin resistance of RNA synthesis in isolated nuclei from Amanita species accumulating amanitins.Arch Microbiol. 1979 Aug 6;122(2):161-7. doi: 10.1007/BF00411355. Arch Microbiol. 1979. PMID: 574756
-
Delayed liver toxicity and delayed gastroenteritis: A 5 year retrospective analysis of the cause of death in Mushroom poisoning.J Family Med Prim Care. 2022 May;11(5):1963-1969. doi: 10.4103/jfmpc.jfmpc_1806_21. Epub 2022 May 14. J Family Med Prim Care. 2022. PMID: 35800559 Free PMC article.
-
Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes.Stud Mycol. 2023 Jul;104:1-85. doi: 10.3114/sim.2022.104.01. Epub 2023 Jan 31. Stud Mycol. 2023. PMID: 37351542 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources