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. 1978 Sep 1;118(3):317-9.
doi: 10.1007/BF00429124.

The insensitivity of mushroom nuclear RNA polymerase activity to inhibition by amatoxins

P A Horgen, A C Vaisius, J F Ammirati

The insensitivity of mushroom nuclear RNA polymerase activity to inhibition by amatoxins

P A Horgen et al. Arch Microbiol. .

Abstract

Nuclear fractions isolated from Amanita phalloides, Amanita muscaria and Agaricus bisporus were subjected to in vitro RNA synthesis assays in the presence of various concentrations of amatoxins. The mushroom nuclei were highly insensitive to inhibition by amatoxin when compared to assays of nuclear fractions isolated from the Oömycete fungus, Achlya ambisexualis and from rabbit brain.

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