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. 1978 Dec;136(3):955-9.
doi: 10.1128/jb.136.3.955-959.1978.

Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product

P Pan, B Wurster

Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product

P Pan et al. J Bacteriol. 1978 Dec.

Abstract

Enzymes inactivating the chemoattractants folic acid and pterin were detected in extracellular, intracellular, and particulate fractions obtained from Dictyostelium discoideum strains NC4 and AX-2 and Polysphondylium violaceum. The products of the inactivation reaction were analyzed by thin-layer chromatography and UV spectroscopy. Results obtained indicate that folic acid and pterin were deaminated to 2-deamino folic acid and lumazine, respectively.

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