Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product
- PMID: 569146
- PMCID: PMC218530
- DOI: 10.1128/jb.136.3.955-959.1978
Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product
Abstract
Enzymes inactivating the chemoattractants folic acid and pterin were detected in extracellular, intracellular, and particulate fractions obtained from Dictyostelium discoideum strains NC4 and AX-2 and Polysphondylium violaceum. The products of the inactivation reaction were analyzed by thin-layer chromatography and UV spectroscopy. Results obtained indicate that folic acid and pterin were deaminated to 2-deamino folic acid and lumazine, respectively.
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