[Methods of determination of the turnover rate of neuromediators (author's transl)]

Abstract

For the study of the effect of a treatment on a neuromediator, the determination of the turnover rate is often more interesting than the determination of the endogenous level of the mediator. Many methods have been used and they are not always isotopic ones. The principal methods are summarized here, especially for catecholamines and serotonin.