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. 1968 Nov;15(5):671-9.

The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs

J K Dineen, P M Ronai, B M Wagland

The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs

J K Dineen et al. Immunology. 1968 Nov.

Abstract

Immune and non-immune mesenteric lymph node and Peyer's patch cells were labelled in vitro with 51Cr and injected intravenously into infected and non-infected syngeneic guinea-pigs (Heston strain). From the distribution of the radioactive label in the small intestine (the site of infection of T. colubriformis) it was concluded that immune lymphocytes: (1) preferentially localize or `home in' on the infection, (2) come into intimate contact with the parasite in the epithelium, and (3) rapidly undergo `allergic death' or lysis at the site of infection.

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References

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