Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1968 Dec;110(3):565-71.
doi: 10.1042/bj1100565.

The biosynthesis of the wall teichoic acid in Staphylococcus lactis I3

J Baddiley, N L Blumsom, L J Douglas

The biosynthesis of the wall teichoic acid in Staphylococcus lactis I3

J Baddiley et al. Biochem J. 1968 Dec.

Abstract

1. The biosynthesis of the wall teichoic acid in Staphylococcus lactis I3 was studied. Cell-free particulate enzyme preparations, probably representing fragmented membrane, were isolated and used for the synthesis of polymer. 2. By using appropriately labelled CDP-glycerol and UDP-N-acetylglucosamine it was shown that the former contributes a glycerol phosphate residue and the latter contributes an N-acetylglucosamine 1-phosphate residue to the repeating unit. 3. No polymer was synthesized unless both nucleotides were present, and no other substrates were required. 4. The properties of the enzyme system were studied. 5. Although attempts to fractionate the system failed, the biosynthesis is believed to be complex and its mechanism is considered.

PubMed Disclaimer

References

    1. Biochem J. 1968 Dec;110(3):543-57 - PubMed
    1. Biochem J. 1968 Dec;110(3):559-63 - PubMed
    1. J Biol Chem. 1958 Jan;230(1):497-509 - PubMed
    1. Biochemistry. 1964 Jul;3:976-80 - PubMed
    1. Nature. 1950 Sep 9;166(4219):444-5 - PubMed

MeSH terms