Morphologic classification of inflammatory, nonspecific, and proliferative lesions of the urinary bladder of mice

Abstract

A morphologic classification of inflammatory, nonspecific, and proliferative lesions of the urinary bladder of mice has been developed. The system was developed over a period of several years in order to tabulate and summarize the lesions for review. The classification has successfully met the needs of the National Center for Toxicological Research and has also provided useful information in understanding the biologic significance of urothelial lesions in mice.