Employment of bis-intercalating dyes for the "in situ" study of DNA composition
- PMID: 574384
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Employment of bis-intercalating dyes for the "in situ" study of DNA composition
Basic Appl Histochem.
1979.
Abstract
Spectrofluorometric characteristics of DNA-RO4 complexes have been studied in order to evaluate the possibility of employment of RO4 (a bis-intercalating dye) for the determination of the DNA base composition. The results have shown the usefulness of this compound for DNA with AT percentage between 30% and 60%. RO4 has been also applied to the study of the chromosome banding mechanism.
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