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Comparative Study
. 1976 May 8;1(7967):990-1.
doi: 10.1016/s0140-6736(76)91862-6.

Cystic fibrosis heterozygosity in the pathogenesis of allergy

J O Warner, A P Norman, J F Soothill
Comparative Study

Cystic fibrosis heterozygosity in the pathogenesis of allergy

J O Warner et al. Lancet. .

Abstract

47% of cystic fibrosis (C.F.) heterozygotes had positive prick skin tests of 1 or more of 9 antigens and 53% had histories of allergic disease, both occurring significantly more often than in a control group. Since 1 in 20 of the population are C.F. carriers, this would contribute to allergy in the community.

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