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. 1969 Feb;111(3):297-301.
doi: 10.1042/bj1110297.

The cryptic nature of hepatic microsomal sulphite oxidase

V C Joshi, C K Kurup, T Ramasarma

The cryptic nature of hepatic microsomal sulphite oxidase

V C Joshi et al. Biochem J. 1969 Feb.

Abstract

1. The activity of rat liver microsomal sulphite oxidase (EC 1.8.3.1) was increased several-fold on aging of microsomes, on delipidation by extraction with acetone or on solubilization with deoxycholate, suggesting its existence in a cryptic state. 2. In rat liver most of the sulphite oxidase was present in the nuclear fraction and only a small portion in the microsomes. 3. Microsomal sulphite oxidase activity was low in the developing embryo and increased rapidly after birth.

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