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. 1977 Apr;101(4):206-7.

Aspirin- and bile- induced acute erosive gastritis: its prevention by metiamide therapy

  • PMID: 576788

Aspirin- and bile- induced acute erosive gastritis: its prevention by metiamide therapy

N S Mann et al. Arch Pathol Lab Med. 1977 Apr.

Abstract

Aspirin or bile administered by esophageal intubation to rats produced acute gastric erosions. These injuries could have been prevented by the prior administration by esophageal intubation of metiamide, a histamine H2 receptor antagonist that is known to inhibit gastric acid secretion.

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